Sodium Hydroxide → 3'-Dimethoxymethylbiphenyl-4-carboxylic acid
Reaction equation
[CH3:1][O:2][CH:3]([O:20][CH3:21])[C:4]1[CH:5]=[C:6]([C:10]2[CH:15]=[CH:14][C:13]([C:16]([O:18]C)=[O:17])=[CH:12][CH:11]=2)[CH:7]=[CH:8][CH:9]=1.[OH-].[Na+]>>[CH3:21][O:20][CH:3]([O:2][CH3:1])[C:4]1[CH:5]=[C:6]([C:10]2[CH:15]=[CH:14][C:13]([C:16]([OH:18])=[O:17])=[CH:12][CH:11]=2)[CH:7]=[CH:8][CH:9]=1Participants
3
Procedure
In a similar manner to that described in Example 2, a reaction was carried out using methyl 3′-dimethoxymethylbiphenyl-4-carboxylate (1.91 g), which is the product of Reference example 14(b), and aqueous sodium hydroxide (1N, 10.0 ml) and the reaction mixture was treated to afford the desired compound (1.55 g) as colorless crystals.
Workup
- additionthe reaction mixture was treated
Sources & evidence
- ORD record