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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1864Generated: October 26, 2026

4-Chloro-5-fluoro-2-propylpyridine → 4-Chloro-3,5-difluoro-2-propyl-pyridine

https://huagongshe.com/reaction/1864

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Chloro-5-fluoro-2-propylpyridineHCID 19691293—
Reactant4-Chloro-5-fluoro-2-methylpyridineHCID 19691410—
Product4-Chloro-3,5-difluoro-2-propyl-pyridineHCID 19691353—

Reaction Steps

By following the procedures described in Example 69 and replacing 4-chloro-5-fluoro-2-picoline (the product of Example 66) with 4-chloro-5-fluoro-2-propyl-pyridine (the product of Example 70), the title compound can be prepared.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05726182
Source datasetuspto-grants-1998_03
ORD IDord-cf330283adb847978dd3b58700a37b8c
Source noteuspto-grants-1998_03