Trimethylamine → N-(5-bromo-4-methylpyridin-2-yl)methanesulfonamide

Reaction equation

[Br:1][c:2]1[c:3]([CH3:9])[cH:4][c:5]([NH2:8])[n:6][cH:7]1.[CH3:10][N:11]([CH3:12])[CH3:13].[CH3:14][S:15]([Cl:16])(=[O:17])=[O:18].[Cl:19][CH2:20][Cl:21]>>[Br:1][c:2]1[c:3]([CH3:9])[cH:4][c:5]([NH:8][S:15]([CH3:14])(=[O:17])=[O:18])[n:6][cH:7]1

Participants

Reactant 4

HCID 1146Trimethylamine

HCID 6344Dichloromethane

HCID 31297Methanesulfonyl chloride

HCID 8176952-Amino-5-bromo-4-methylpyridine

Product 1

HCID 67280818N-(5-bromo-4-methylpyridin-2-yl)methanesulfonamide

Sources & evidence

ORD record: ord-01bdec7d97c046a48bc7cd60cad10776
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (6/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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