Methanol → N-(4-Chloro-3-cyclopropylaminomethyl-benzyl)-3,3,3-trifluoro-propionamide
Reaction equation
[BH4-:23].[CH3:25][OH:26].[CH:19]1([NH2:22])[CH2:20][CH2:21]1.[Cl:1][c:2]1[c:3]([CH:17]=[O:18])[cH:4][c:5]([CH2:6][NH:7][C:8]([CH2:9][C:10]([F:11])([F:12])[F:13])=[O:14])[cH:15][cH:16]1.[Na+:24]>>[Cl:1][c:2]1[c:3]([CH2:17][NH:22][CH:19]2[CH2:20][CH2:21]2)[cH:4][c:5]([CH2:6][NH:7][C:8]([CH2:9][C:10]([F:11])([F:12])[F:13])=[O:14])[cH:15][cH:16]1Participants
6
Sources & evidence
- ORD record
- ord-8170dba2841e4b09802e43167ac4b310
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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