Potassium Hydroxide → HCID 58345423, compound
Reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([N:8]2[C:12]([C:13]3[CH:18]=[CH:17][C:16]([Cl:19])=[CH:15][C:14]=3[Cl:20])=[CH:11][C:10]([C:21]([O:23]CC)=[O:22])=[N:9]2)[CH:5]=[CH:6][CH:7]=1.[OH-].[K+]>>[Cl:1][C:2]1[CH:3]=[C:4]([N:8]2[C:12]([C:13]3[CH:18]=[CH:17][C:16]([Cl:19])=[CH:15][C:14]=3[Cl:20])=[CH:11][C:10]([C:21]([OH:23])=[O:22])=[N:9]2)[CH:5]=[CH:6][CH:7]=1Participants
3
Procedure
Starting from 240 mg (0.61 mmol) of ethyl 1-(3-chlorophenyl)-5-(2,4-dichloro-phenyl)-1H-pyrazole-3-carboxylate from example 18A and 340.3 mg (6.1 mmol) of potassium hydroxide, 204 mg (0.55 mmol, 92% yield of theory) are obtained as crystals according to the method described in example 7A.
Workup
- customare obtained as crystals
Sources & evidence
- ORD record
- ord-e87a488f635648f3bfb28c3f20cad999
- Source dataset