(4-(N-Isopropylsulfamoyl)phenyl)boronic acid → 1-Methylethyl 4-{[(4'-{[(1-methylethyl)amino]sulfonyl}-4-biphenylyl)oxy]methyl}-1-piperidinecarboxylate

HRID 187980

Reaction equation

HRID 187980 reaction equation
[Br:17][c:18]1[cH:19][cH:20][c:21]([O:24][CH2:25][CH:26]2[CH2:27][CH2:28][N:29]([C:32](=[O:33])[O:34][CH:35]([CH3:36])[CH3:37])[CH2:30][CH2:31]2)[cH:22][cH:23]1.[CH3:1][CH:2]([CH3:3])[NH:4][S:5](=[O:6])(=[O:7])[c:8]1[cH:9][cH:10][c:11]([B:14]([OH:15])[OH:16])[cH:12][cH:13]1>>[CH3:1][CH:2]([CH3:3])[NH:4][S:5](=[O:6])(=[O:7])[c:8]1[cH:9][cH:10][c:11](-[c:18]2[cH:19][cH:20][c:21]([O:24][CH2:25][CH:26]3[CH2:27][CH2:28][N:29]([C:32](=[O:33])[O:34][CH:35]([CH3:36])[CH3:37])[CH2:30][CH2:31]3)[cH:22][cH:23]2)[cH:12][cH:13]1

Participants

3

Reactant 2

HCID 44119552(4-(N-Isopropylsulfamoyl)phenyl)boronic acidHCID 579303004-(4-Bromophenoxymethyl)piperidine-1-carboxylic acid isopropyl ester

Product 1

HCID 591777691-Methylethyl 4-{[(4'-{[(1-methylethyl)amino]sulfonyl}-4-biphenylyl)oxy]methyl}-1-piperidinecarboxylate

Sources & evidence

ORD record
ord-68b4e7fa9d8044be98b416e31de2d6c9
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Linked notes

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