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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 188083Generated: October 27, 2026

Water → [2-(2-Fluoro-4-trifluoromethyl-phenyl)-ethyl]-[2-methoxy-6-(3-oxiranylmethoxy-phenyl)-pyrimidin-4-yl]-amine

https://huagongshe.com/reaction/188083

Reaction equation

Participants

RoleNameHCIDCharge
ReactantWaterHCID 962—
ReactantDimethylformamideHCID 6228—
ReactantEpichlorohydrinHCID 7835—
ReactantCarbonate IonHCID 19660—
ReactantCesium cationHCID 104967—
Reactant3-{6-[2-(2-Fluoro-4-trifluoromethyl-phenyl)-ethylamino]-2-methoxy-pyrimidin-4-yl}-phenolHCID 69069566—
Product[2-(2-Fluoro-4-trifluoromethyl-phenyl)-ethyl]-[2-methoxy-6-(3-oxiranylmethoxy-phenyl)-pyrimidin-4-yl]-amineHCID 11705324—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (6/10)
ORD IDord-4b927c0d404943de86cd4efed269d6a2
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (6/10)