2-((Phenylmethyl)thio)acetic acid → HCID 178461345, compound
Reaction equation
ClC1C=C(C[CH2:9][CH2:10][N:11]([C@H:25]2[CH2:30][CH2:29][C@H:28]([CH3:31])[CH2:27][CH2:26]2)[C:12](=[O:24])[NH:13][C:14]2[S:15][C:16]([S:19][CH2:20][C:21]([OH:23])=[O:22])=[CH:17][N:18]=2)C=CC=1.[CH2:32]([S:39]CC(O)=O)[C:33]1[CH:38]=[CH:37][CH:36]=[CH:35][CH:34]=1.C(OC(=O)CSC1SC(N)=NC=1)C>>[CH2:32]([S:39][CH2:9][CH2:10][N:11]([C@H:25]1[CH2:26][CH2:27][C@H:28]([CH3:31])[CH2:29][CH2:30]1)[C:12](=[O:24])[NH:13][C:14]1[S:15][C:16]([S:19][CH2:20][C:21]([OH:23])=[O:22])=[CH:17][N:18]=1)[C:33]1[CH:38]=[CH:37][CH:36]=[CH:35][CH:34]=1Participants
4
Procedure
The compound was prepared following an analogous procedure to the one described for the synthesis of {2-[-3-[3-(3-chloro-phenyl)-propyl]-3-(trans-4-methyl -cyclohexyl)-ureido]-thiazol-5-ylsulfanyl}-acetic acid using benzylsulfanyl-acetic acid and (2-aminothiazol-5-ylsulfanyl) acetic acid ethyl ester.