Acetonitrile → 4-[4-(Methylsulfonyl)phenyl]-N-(pyridin-2-ylmethyl)-6-(trifluoromethyl)pyrimidin-2-amine

HRID 188113

Reaction equation

HRID 188113 reaction equation
[CH3:1][S:2](=[O:3])(=[O:4])[c:5]1[n:6][c:7]([C:21]([F:22])([F:23])[F:24])[cH:8][c:9](-[c:11]2[cH:12][cH:13][c:14]([S:17](=[O:18])(=[O:19])[CH3:20])[cH:15][cH:16]2)[n:10]1.[CH3:33][C:34]#[N:35].[NH2:25][CH2:26][c:27]1[n:28][cH:29][cH:30][cH:31][cH:32]1>>[c:5]1([NH:25][CH2:26][c:27]2[n:28][cH:29][cH:30][cH:31][cH:32]2)[n:6][c:7]([C:21]([F:22])([F:23])[F:24])[cH:8][c:9](-[c:11]2[cH:12][cH:13][c:14]([S:17](=[O:18])(=[O:19])[CH3:20])[cH:15][cH:16]2)[n:10]1

Participants

4

Reactant 3

HCID 6342AcetonitrileHCID 195092-PyridinemethanamineHCID 111764432-(Methylsulfonyl)-4-[4-(methylsulfonyl)phenyl]-6-(trifluoromethyl)pyrimidine

Product 1

HCID 102231534-[4-(Methylsulfonyl)phenyl]-N-(pyridin-2-ylmethyl)-6-(trifluoromethyl)pyrimidin-2-amine

Sources & evidence

ORD record
ord-0504fee76f2b4ab8b33102ec44dcbb66
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Linked notes

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