5-Aminoindole → Octahydro-1H-indol-5-amine

HRID 1883

Reaction equation

HRID 1883 reaction equation
[NH2:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[NH:7][CH:6]=[CH:5]2>C(O)(=O)C>[NH2:1][CH:2]1[CH2:10][CH2:9][CH:8]2[CH:4]([CH2:5][CH2:6][NH:7]2)[CH2:3]1

Participants

3

Reactant 1

HCID 788675-Aminoindole

Product 1

HCID 19691325Octahydro-1H-indol-5-amine

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

A 1.0 g sample of 5-aminoindole was hydrogenated at 4 atm H2 in 50 mL of acetic acid over 2 g of Pt2O at room temperature for 90 hours. The solution was filtered, and the solvent was removed

Workup

  1. filtrationThe solution was filtered
  2. customthe solvent was removed

Sources & evidence

ORD record
ord-93761b963a124e92971caa48a87616c1
Source dataset
uspto-grants-1998_03
Patent number
US05726182

Linked notes

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