2-Hydroxy-11-cycloeicosenone → 2-Hydroxycyclotetracosanone

HRID 1883292

Reaction equation

HRID 1883292 reaction equation
OC1CCCCCCCCC=CCCCCCCCCC1=O.[OH:23][CH:24]1[CH2:47][CH2:46][CH2:45][CH2:44][CH2:43][CH2:42][CH2:41][CH2:40][CH2:39][CH2:38][CH:37]=[CH:36][CH2:35][CH2:34][CH2:33][CH2:32][CH2:31][CH2:30][CH2:29][CH2:28][CH2:27][CH2:26][C:25]1=[O:48]>>[OH:48][CH:25]1[CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][CH2:38][CH2:39][CH2:40][CH2:41][CH2:42][CH2:43][CH2:44][CH2:45][CH2:46][CH2:47][C:24]1=[O:23]

Participants

3

Reactant 2

HCID 673128522-Hydroxy-11-cycloeicosenoneHCID 673128572-Hydroxy-13-cyclotetracosenone

Product 1

HCID 134294212-HydroxycyclotetracosanoneYield 99.4%

Procedure

2-Hydroxy-11-cycloeicosenone of Synthesis Example 7 was replaced by 2-hydroxy-13-cyclotetracosenone (0.70 g, 1.92 mmol). The latter was subjected to a hydrogenation reaction and subsequent treatment under the same conditions as in Synthesis Example 7, to give 0.70 g of 2-hydroxycyclotetracosanone (quantitative yield).

Workup

  1. customThe latter was subjected to a hydrogenation reaction and subsequent treatment under the same conditions as in Synthesis Example 7

Sources & evidence

ORD record
ord-6b50af9cd1d5494caaf2b6246d452057
Source dataset
uspto-grants-2004_07
Patent number
US06759557B2

Linked notes

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