3,5-Dichloro-4-amino-benzoate → 2,6-Dichloroaniline
Reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([CH:8]=[C:9]([Cl:12])[C:10]=1[NH2:11])C([O-])=O>O>[Cl:1][C:2]1[CH:3]=[CH:4][CH:8]=[C:9]([Cl:12])[C:10]=1[NH2:11]Participants
3
Reagents, catalysts & solvents 1
Conditions
- Temperature
- 250 °C
Procedure
0.2 mole=41.2 g 3,5-dichloro-4-amino-benzoate were initially introduced into an autoclave together with 250 ml of water. The mixture was heated to 250° C. and stirred at this temperature for eight hours. The product was then recovered by steam distillation. 26 g of 2,6-dichloroaniline were obtained in a purity of 99.8%, corresponding to a yield of 80%.
Workup
- distillationThe product was then recovered by steam distillation
Sources & evidence
- ORD record
- ord-8a54934bbb3345daa446f4755cede81a
- Source dataset
- uspto-grants-1992_09
- Patent number
- US05145958
Reaction notes
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