1-Cyclopentylpiperazine → 1-{4-[6-(4-Cyclopentylpiperazin-1-yl)pyridin-3-yl]phenyl}ethanone, dihydrochloride

HRID 1887111

Reaction equation

HRID 1887111 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[CH:13]=[CH:12][C:11]([C:14](=[O:16])[CH3:15])=[CH:10][CH:9]=2)=[CH:4][N:3]=1.[CH:17]1([N:22]2[CH2:27][CH2:26][NH:25][CH2:24][CH2:23]2)[CH2:21][CH2:20][CH2:19][CH2:18]1>>[ClH:1].[ClH:1].[CH:17]1([N:22]2[CH2:23][CH2:24][N:25]([C:2]3[N:3]=[CH:4][C:5]([C:8]4[CH:13]=[CH:12][C:11]([C:14](=[O:16])[CH3:15])=[CH:10][CH:9]=4)=[CH:6][CH:7]=3)[CH2:26][CH2:27]2)[CH2:18][CH2:19][CH2:20][CH2:21]1

Participants

3

Reactant 2

HCID 8064211-CyclopentylpiperazineHCID 872859922-Chloro-5-(4-acetylphenyl)pyridine

Product 1

HCID 1317307611-{4-[6-(4-Cyclopentylpiperazin-1-yl)pyridin-3-yl]phenyl}ethanone, dihydrochloride

Procedure

The title compound was prepared by a similar procedure to that described in Example 1, starting from 2-chloro-5-(4-acetylphenyl)pyridine and 1-cyclopentylpiperazine.

Sources & evidence

ORD record
ord-ec693ee7eb7447448058e67c71e75d51
Source dataset
uspto-grants-2013_08
Patent number
US08501739B2

Linked notes

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