4-(1H-1,2,4-triazol-5-yl)benzoic acid → HCID 71208683, compound
Reaction equation
[NH2:1][CH2:2][C:3]1[C:12](=[O:13])[C:11]2[C:6](=[CH:7][C:8]([Cl:14])=[CH:9][CH:10]=2)[N:5]([C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=2)[CH:4]=1.[N:21]1[NH:22][C:23]([C:26]2[CH:34]=[CH:33][C:29]([C:30](O)=[O:31])=[CH:28][CH:27]=2)=[N:24][CH:25]=1>>[Cl:14][C:8]1[CH:7]=[C:6]2[C:11]([C:12](=[O:13])[C:3]([CH2:2][NH:1][C:30](=[O:31])[C:29]3[CH:28]=[CH:27][C:26]([C:23]4[NH:22][N:21]=[CH:25][N:24]=4)=[CH:34][CH:33]=3)=[CH:4][N:5]2[C:15]2[CH:16]=[CH:17][CH:18]=[CH:19][CH:20]=2)=[CH:10][CH:9]=1Participants
3
Procedure
N-(7-Chloro-4-oxo-1-phenyl-1,4-dihydro-quinolin-3-ylmethyl)-4-(2H-[1,2,4]triazol-3-yl)-benzamide was prepared starting from intermediate D and 4-(2H-[1,2,4]triazol-3-yl)-benzoic acid. MS calcd. for C25H18ClN5O2 [(M+H)+] 455.9, obsd. 456.0.
Sources & evidence
- ORD record
- ord-6026fc4a279147db9d31cbb9237078ca
- Source dataset
- uspto-grants-2013_08