3,4,5-Trimethoxybenzaldehyde → HCID 178492117, compound

HRID 1888954

Reaction equation

HRID 1888954 reaction equation
[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([N:8]2[CH2:12][CH2:11][CH2:10][CH2:9]2)=[CH:4][C:3]=1[NH:13][C:14](=[O:21])[C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1.[CH3:22][O:23][C:24]1[CH:25]=[C:26]([CH:29]=[C:30]([O:34][CH3:35])[C:31]=1[O:32][CH3:33])[CH:27]=O>CO>[N:8]1([C:5]2[CH:6]=[CH:7][C:2](/[N:1]=[CH:27]/[C:26]3[CH:29]=[C:30]([O:34][CH3:35])[C:31]([O:32][CH3:33])=[C:24]([O:23][CH3:22])[CH:25]=3)=[C:3]([NH:13][C:14](=[O:21])[C:15]3[CH:16]=[CH:17][CH:18]=[CH:19][CH:20]=3)[CH:4]=2)[CH2:9][CH2:10][CH2:11][CH2:12]1

Participants

4

Reactant 2

HCID 68583,4,5-TrimethoxybenzaldehydeHCID 68515788N-(2-amino-5-(pyrrolidin-1-yl)phenyl)benzamide

Product 1

HCID 178492117HCID 178492117, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

A mixture of N-(2-amino-5-(pyrrolidin-1-yl)phenyl)benzamide (2 mmol) and 3,4,5-trimethoxybenzaldehyde (3 mmol) in methanol was stirred at room temperature for 12 h. The suspension was filtered and the solid was washed with methanol to afford (E)-N-(5-(pyrrolidin-1-yl)-2-(3,4,5-trimethoxybenzylideneamino)phenyl)benzamide as a yellow solid.

Workup

  1. filtrationThe suspension was filtered
  2. washthe solid was washed with methanol

Sources & evidence

ORD record
ord-f9f3e722f3574204b664c4ca1e296603
Source dataset
uspto-grants-2013_08
Patent number
US08501957B2

Linked notes

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