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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 18892Generated: October 26, 2026

2-Amino-5-chlorobenzophenone → N-(2-Benzoyl4-chloro-phenyl)4-trifluoromethoxy-benzenesulfonamide

https://huagongshe.com/reaction/18892

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Amino-5-chlorobenzophenoneHCID 12870—
Reactantp-(Trifluoromethoxy)benzenesulphonyl chlorideHCID 523102—
ProductN-(2-Benzoyl4-chloro-phenyl)4-trifluoromethoxy-benzenesulfonamideHCID 10321805—

Reaction Steps

The title compound was prepared according to the general procedure for the synthesis of N-Aryl-benzenesulfonamides previously described using (2-amino-5-chloro-phenyl)-phenyl-methanone and 4-Trifluoromethoxy-benzenesulfonyl chloride. 1H NMR (CDCl3): δ 7.06 (d, J=8.0 Hz, 2H), 7.36 (m, 3H), 7.40-7.44 (m, 2H), 7.49 & 7.62 (dd, J=8.8 Hz, 2.0 Hz, 1H), 7.58-7.62 (m, 1H), 7.70 (d, J=8.8 Hz, 2H), 7.70 (d, J=8.8 Hz, 1H), 9.81 (s, 1H). MS: m/z 456.0 (M++1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07741519B2
Source datasetuspto-grants-2010_06
ORD IDord-8062ece2cfc94a04b0d411ae947f3109
Source noteuspto-grants-2010_06