HuagongsheHuagongshe Chemistry Print Report · For research reference only
3,5-Dichlorophenyl isocyanate → N-(3,5-Dichlorophenyl)-2-(4,8-dimethylquinolin-2-yl)hydrazinecarboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3,5-Dichlorophenyl isocyanate | HCID 94460 | — |
| Reactant | 2-Hydrazinyl-4,8-dimethylquinoline | HCID 3684316 | — |
| Product | N-(3,5-Dichlorophenyl)-2-(4,8-dimethylquinolin-2-yl)hydrazinecarboxamide | HCID 52912061 | — |
Reaction Steps
A solution of 2-hydrazinyl-4,8-dimethylquinoline (100 mg, 0.53 mmol) and 100 mg (1.0 eq) of 1,3-dichloro-5-isocyanatobenzene was reacted as outlined in Scheme 1 above to give the desired title compound. Spectroscopic data: 1H NMR (300 MHz, DMSO-d6) δ ppm 2.51 (s, 3 H) 2.55 (s, 3 H) 6.77-6.80 (m, 1 H) 7.09 (t, J=1.76 Hz, 1 H) 7.17 (dd, J=8.20, 7.03 Hz, 1 H) 7.40 (d, J=6.74 Hz, 1 H) 7.65-7.72 (m, 3 H) 8.40 (br. s., 1 H) 8.62 (s, 1 H) 9.25 (br. s., 1 H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08507682B2 |
| Source dataset | uspto-grants-2013_08 |
| ORD ID | ord-dc8835d90a7743f391887015b90e7de4 |
| Source note | uspto-grants-2013_08 |