1,4-Dioxaspiro[4.5]decan-8-one → 8-[4-(tert-Butyl-dimethyl-silanyloxy)-phenyl]-1,4-dioxa-spiro[4.5]decan-8-ol

HRID 1893263

Reaction equation

HRID 1893263 reaction equation
Br[C:2]1[CH:15]=[CH:14][C:5]([O:6][Si:7]([C:10]([CH3:13])([CH3:12])[CH3:11])([CH3:9])[CH3:8])=[CH:4][CH:3]=1.[O:16]1[C:20]2([CH2:25][CH2:24][C:23](=[O:26])[CH2:22][CH2:21]2)[O:19][CH2:18][CH2:17]1>>[C:10]([Si:7]([CH3:9])([CH3:8])[O:6][C:5]1[CH:14]=[CH:15][C:2]([C:23]2([OH:26])[CH2:24][CH2:25][C:20]3([O:19][CH2:18][CH2:17][O:16]3)[CH2:21][CH2:22]2)=[CH:3][CH:4]=1)([CH3:13])([CH3:12])[CH3:11]

Participants

3

Reactant 2

HCID 5674151,4-Dioxaspiro[4.5]decan-8-oneHCID 4227167(4-Bromophenoxy)(tert-butyl)dimethylsilane

Product 1

HCID 595419828-[4-(tert-Butyl-dimethyl-silanyloxy)-phenyl]-1,4-dioxa-spiro[4.5]decan-8-ol

Procedure

The title compound was prepared as a white solid from (4-bromo-phenoxy)-tert-butyl-dimethyl-silane (Aldrich) and 1,4-dioxa-spiro[4.5]decan-8-one using the procedure described in Step A of Example 1.

Sources & evidence

ORD record
ord-4d8f79bf60fe462396770706787e83d9
Source dataset
uspto-grants-2013_08
Patent number
US08513229B2

Linked notes

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