Acetonitrile → 5,10-Dihydro-5-[6-(1-piperidinyl)-hexyl]-11H-dibenzo[b,e][1,4]diazepin-11-one

HRID 190020

Reaction equation

HRID 190020 reaction equation
[Br:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][N:29]1[CH2:30][CH2:31][CH2:32][CH2:33][CH2:34]1.[CH2:17]([Li:18])[CH2:19][CH2:20][CH3:21].[CH3:35][C:36]#[N:37].[cH:1]1[cH:2][cH:3][cH:4][c:5]2[c:11]1[C:10](=[O:12])[NH:9][c:8]1[c:7]([cH:16][cH:15][cH:14][cH:13]1)[NH:6]2>>[cH:1]1[cH:2][cH:3][cH:4][c:5]2[c:11]1[C:10](=[O:12])[NH:9][c:8]1[c:7]([cH:16][cH:15][cH:14][cH:13]1)[N:6]2[CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][N:29]1[CH2:30][CH2:31][CH2:32][CH2:33][CH2:34]1

Participants

5

Reactant 4

HCID 6342AcetonitrileHCID 2013275,10-Dihydro-11H-dibenzo(b,e)(1,4)diazepin-11-oneHCID 200624841-Bromo6-(1-piperidinyl)hexaneHCID 178418339Butyllithium

Product 1

HCID 145521025,10-Dihydro-5-[6-(1-piperidinyl)-hexyl]-11H-dibenzo[b,e][1,4]diazepin-11-one

Sources & evidence

ORD record
ord-f0d7284e5b274f7b958a87e00245e55f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Linked notes

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