M-Cresol → 7-Bromo-4-(4-fluorophenyl)-chromen-2-one

HRID 1901129

Reaction equation

HRID 1901129 reaction equation
CCN([C:6]1[CH:11]=[CH:10][C:9]2[C:12]([CH3:17])=[CH:13][C:14]([O:16][C:8]=2[CH:7]=1)=[O:15])CC.C1C(O)=CC=CC=1C.[F:26][C:27]1[CH:32]=[CH:31]C(I)=[CH:29][CH:28]=1.[Br:34]C1C=COC=1>>[F:26][C:27]1[CH:32]=[CH:31][C:17]([C:12]2[C:9]3[C:8](=[CH:7][C:6]([Br:34])=[CH:11][CH:10]=3)[O:16][C:14](=[O:15])[CH:13]=2)=[CH:29][CH:28]=1

Participants

5

Reactant 4

HCID 342M-CresolHCID 70504-Methyl-7-diethylaminocoumarinHCID 96054-FluoroiodobenzeneHCID 891643-Bromofuran

Product 1

HCID 233702437-Bromo-4-(4-fluorophenyl)-chromen-2-one

Procedure

Following the procedures described for Coumarin 1, Steps 1 to 5, but substituting 3-bromophenol for m-cresol and 4-fluoroiodobenzene for 3-bromofuran, the title compound was obtained.

Sources & evidence

ORD record
ord-ec305fa3cff14bc0ac9fa4beb0ac4e8f
Source dataset
uspto-grants-1996_11
Patent number
US05576338

Linked notes

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