Reaction equation
[NH2:1][C:2]1[C:16]([CH2:17][N:18]2[CH2:23][CH2:22][CH2:21][CH2:20][CH2:19]2)=[CH:15][C:5]([C:6]([O:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13]Cl)=[O:7])=[CH:4][C:3]=1[Br:24].[Cl:25][C:26]1[CH:31]=[CH:30][CH:29]=[C:28]([Cl:32])[C:27]=1[NH:33][C:34]1[CH:39]=[CH:38][CH:37]=[CH:36][C:35]=1[CH2:40][C:41]([O-:43])=[O:42].[Na+]>>[NH2:1][C:2]1[C:16]([CH2:17][N:18]2[CH2:23][CH2:22][CH2:21][CH2:20][CH2:19]2)=[CH:15][C:5]([C:6]([O:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][O:43][C:41](=[O:42])[CH2:40][C:35]2[CH:36]=[CH:37][CH:38]=[CH:39][C:34]=2[NH:33][C:27]2[C:26]([Cl:25])=[CH:31][CH:30]=[CH:29][C:28]=2[Cl:32])=[O:7])=[CH:4][C:3]=1[Br:24]Participants
3
Procedure
This compound was prepared from 5-(4-amino-3-bromo-5-piperidinomethyl-benzoyloxy)-n-pentyl chloride and sodium 2-[(2,6-dichlorophenyl)-amino]-phenylacetate analogous to Example 8.
Sources & evidence
- ORD record
- ord-d956c8963a644f15b7e156398fef9fa6
- Source dataset
- uspto-grants-1982_12
- Patent number
- US04362738
Linked notes
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