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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1906147Generated: October 27, 2026

Sulfuric Acid → 2-(4-Chlorophenyl)-3-benzoylaminomethyl-6-methylimidazo[1,2-a]pyridine

https://huagongshe.com/reaction/1906147

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSulfuric AcidHCID 1118—
ReactantN-(hydroxymethyl)benzamideHCID 80493—
Reactant2-(4-Chlorophenyl)-6-methylimidazo[1,2-a]pyridineHCID 735911—
SolventAcetic AcidHCID 176—
Product2-(4-Chlorophenyl)-3-benzoylaminomethyl-6-methylimidazo[1,2-a]pyridineHCID 13589589—

Reaction Conditions

Temperature50 °C

Reaction Steps

To a solution of 4.54 g (0.03 mol) of N-(hydroxymethyl)benzamide in 50 ml of glacial acetic acid, 2 g of concentrated sulphuric acid are added, and then, after 15 minutes' heating at 50° C., 4.8 g (0.02 mol) of 2-(4-chlorophenyl)-6-methylimidazo[1,2-a]pyridine are added.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04650796
Source datasetuspto-grants-1987_03
ORD IDord-f09ddaa63a2d4d9f960d9774a8536c03
Source noteuspto-grants-1987_03