4-Fluoro-3-(trifluoromethyl)benzenesulfonyl Chloride → 4-Fluoro-N-[6-(4-fluoro-benzyloxymethyl)-pyridin-2-yl]-3-trifluoromethyl-benzenesulfonamide

HRID 190694

Reaction equation

HRID 190694 reaction equation
[F:18][c:19]1[c:20]([C:29]([F:30])([F:31])[F:32])[cH:21][c:22]([S:25](=[O:26])(=[O:27])[Cl:28])[cH:23][cH:24]1.[F:1][c:2]1[cH:3][cH:4][c:5]([CH2:6][O:7][CH2:8][c:9]2[cH:10][cH:11][cH:12][c:13]([NH2:15])[n:14]2)[cH:16][cH:17]1>>[F:1][c:2]1[cH:3][cH:4][c:5]([CH2:6][O:7][CH2:8][c:9]2[cH:10][cH:11][cH:12][c:13]([NH:15][S:25]([c:22]3[cH:21][c:20]([C:29]([F:30])([F:31])[F:32])[c:19]([F:18])[cH:24][cH:23]3)(=[O:26])=[O:27])[n:14]2)[cH:16][cH:17]1

Participants

3

Reactant 2

HCID 27375494-Fluoro-3-(trifluoromethyl)benzenesulfonyl ChlorideHCID 688451406-(4-Fluoro-benzyloxymethyl)-pyridin-2-ylamine

Product 1

HCID 688461924-Fluoro-N-[6-(4-fluoro-benzyloxymethyl)-pyridin-2-yl]-3-trifluoromethyl-benzenesulfonamide

Sources & evidence

ORD record
ord-641f007a9c554ccaa332e883de429154
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Linked notes

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