HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(3,5-Dimethoxyphenyl)piperazine → 1-[(6,7-Difluoro-2-methoxyquinoxalin-3-yl)aminocarbonyl]-4-(3,5-dimethoxyphenyl)piperazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(3,5-Dimethoxyphenyl)piperazine | HCID 2736205 | — |
| Reactant | Ethyl N-(6,7-difluoro-2-methoxyquinoxalin-3-yl)carbamate | HCID 69244192 | — |
| Product | 1-[(6,7-Difluoro-2-methoxyquinoxalin-3-yl)aminocarbonyl]-4-(3,5-dimethoxyphenyl)piperazine | HCID 69240969 | 70% |
Reaction Steps
Ethyl N-(6,7-difluoro-2-methoxyquinoxalin-3-yl)carbamate and 1-(3,5-dimethoxyphenyl)piperazine were reacted by the same way with the example 169 to obtain the titled compound (yield, 70%). MS (ESI) m/z 460 ([M+H]+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08598173B2 |
| Source dataset | uspto-grants-2013_12 |
| ORD ID | ord-f77c301f105b4daca8e884174415bea0 |
| Source note | uspto-grants-2013_12 |