Methanol → Tert-butyl 4-{[2-({3-amino-5-[2-(1-hydroxycyclobutyl)-1,3-thiazol-5-yl]phenyl}amino)pyrimidin-4-yl]-oxy}piperidine-1-carboxylate
Reaction equation
[CH3:41][OH:42].[OH:1][C:2]1([c:6]2[s:7][c:8](-[c:11]3[cH:12][c:13]([NH:20][c:21]4[n:22][cH:23][cH:24][c:25]([O:27][CH:28]5[CH2:29][CH2:30][N:31]([C:34](=[O:35])[O:36][C:37]([CH3:38])([CH3:39])[CH3:40])[CH2:32][CH2:33]5)[n:26]4)[cH:14][c:15]([N+:17]([O-:18])=[O:19])[cH:16]3)[cH:9][n:10]2)[CH2:3][CH2:4][CH2:5]1>>[OH:1][C:2]1([c:6]2[s:7][c:8](-[c:11]3[cH:12][c:13]([NH:20][c:21]4[n:22][cH:23][cH:24][c:25]([O:27][CH:28]5[CH2:29][CH2:30][N:31]([C:34](=[O:35])[O:36][C:37]([CH3:38])([CH3:39])[CH3:40])[CH2:32][CH2:33]5)[n:26]4)[cH:14][c:15]([NH2:17])[cH:16]3)[cH:9][n:10]2)[CH2:3][CH2:4][CH2:5]1Participants
3
Sources & evidence
- ORD record
- ord-f5040920921d43a29844b80f5df0ae1b
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
Loading…