Tetrachlorophthalic anhydride → Fthalide

HRID 1911952

Reaction equation

[Cl:1][C:2]1[C:3]([Cl:15])=[C:4]([Cl:14])[C:5]([Cl:13])=[C:6]2[C:11](=O)[O:10][C:8](=[O:9])[C:7]=12.[H-].[Al+3].[Li+].[H-].[H-].[H-]>>[Cl:13][C:5]1[C:4]([Cl:14])=[C:3]([Cl:15])[C:2]([Cl:1])=[C:7]2[C:6]=1[CH2:11][O:10][C:8]2=[O:9]

Participants

Reactant 2

HCID 8326Tetrachlorophthalic anhydride

HCID 21226445Aluminium lithium hydride

Product 1

HCID 33791Fthalide

Procedure

Gazzetta Chimica Italiana, 87, p. 1147 (1957) describes, as a method for producing a halogen-substituted phthalide, for example, a method in which tetrachlorophthalic anhydride is reacted with lithium aluminum hydride to obtain 4,5,6,7-tetrachloro-1(3H)-isobenzofuranone.

Sources & evidence

ORD record: ord-16e0221035c84f78b8625ef505ed8837
Source dataset: uspto-grants-2013_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08604221B2

Linked notes

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