(3-Methoxyphenyl)boronic acid → 8-(3-Methoxyphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-ylamine

HRID 1913095

Reaction equation

HRID 1913095 reaction equation
FC(F)(F)[C:3]1[CH:4]=[C:5]([C:9]2[C:10]3[N:11]([N:15]=[C:16]([NH2:18])[N:17]=3)[CH:12]=[CH:13][CH:14]=2)[CH:6]=[CH:7][CH:8]=1.[CH3:21][O:22]C1C=C(B(O)O)C=CC=1>>[CH3:21][O:22][C:3]1[CH:4]=[C:5]([C:9]2[C:10]3[N:11]([N:15]=[C:16]([NH2:18])[N:17]=3)[CH:12]=[CH:13][CH:14]=2)[CH:6]=[CH:7][CH:8]=1

Participants

3

Reactant 2

HCID 2734370(3-Methoxyphenyl)boronic acidHCID 591990748-(3-Trifluoromethylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-ylamine

Product 1

HCID 591991028-(3-Methoxyphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-ylamine

Procedure

Made by following the procedure described for the preparation of 8-(3-(trifluoromethyl)phenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine but substituting 3-methoxyphenyl boronic acid and making non-critical variations.

Sources & evidence

ORD record
ord-811adac0e47240d6800dac247c304590
Source dataset
uspto-grants-2013_12
Patent number
US08609687B2

Linked notes

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