3-Aminoquinuclidine → N-(1-azabicyclo[2.2.2]octan-3-yl)-6,7,8,9-tetrahydropyrido[1,2-a]indole-1-carboxamide

HRID 191621

Reaction equation

HRID 191621 reaction equation
[CH3:10][n:11]1[c:12]2[c:13]([cH:14][cH:15][cH:16][cH:17]2)[c:18]([C:19]([O:20][CH2:21][CH3:22])=[O:23])[c:24]1[CH3:25].[NH2:1][CH:2]1[CH2:3][N:4]2[CH2:5][CH2:6][CH:7]1[CH2:8][CH2:9]2.[c:26]1([C:39](=[O:40])[O:41][CH3:42])[c:27]2[cH:28][c:29]3[n:30]([c:31]2[cH:32][cH:33][cH:34]1)[CH2:35][CH2:36][CH2:37][CH2:38]3>>[NH:1]([CH:2]1[CH2:3][N:4]2[CH2:5][CH2:6][CH:7]1[CH2:8][CH2:9]2)[C:39]([c:26]1[c:27]2[cH:28][c:29]3[n:30]([c:31]2[cH:32][cH:33][cH:34]1)[CH2:35][CH2:36][CH2:37][CH2:38]3)=[O:40]

Participants

4

Reactant 3

HCID 1232383-AminoquinuclidineHCID 599139Ethyl 1,2-dimethyl-1H-indole-3-carboxylateHCID 19778122Methyl 6,7,8,9-tetrahydropyrido[1,2-a]indole-1-carboxylate

Product 1

HCID 19778098N-(1-azabicyclo[2.2.2]octan-3-yl)-6,7,8,9-tetrahydropyrido[1,2-a]indole-1-carboxamide

Sources & evidence

ORD record
ord-f2a801c402b54d308af278f8830964ac
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Linked notes

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