Nitric Acid → HCID 178512968, compound

HRID 1924884Notes

Reaction equation

HRID 1924884 reaction equation
[N+:1]([O-:4])([OH:3])=[O:2].[NH2:5][C:6](=[NH:13])[NH:7][CH2:8][CH2:9][CH2:10][CH2:11][NH2:12].[N+:14]([O-:17])([OH:16])=[O:15].[NH2:18][C:19](=[NH:26])[NH:20][CH2:21][CH2:22][CH2:23][CH2:24][NH2:25]>O>[N+:1]([O-:4])([OH:3])=[O:2].[N+:14]([O-:17])([OH:16])=[O:15].[NH2:13][C:6](=[NH:5])[NH:7][CH2:8][CH2:9][CH2:10][CH2:11][NH2:12].[N+:1]([O-:4])([OH:3])=[O:2].[N+:1]([O-:4])([OH:3])=[O:2].[N+:1]([O-:4])([OH:3])=[O:2].[NH2:26][C:19](=[NH:18])[NH:20][CH2:21][CH2:22][CH2:23][CH2:24][NH2:25]

Participants

6

Reactant 3

HCID 944Nitric AcidHCID 178512945HCID 178512945, compoundHCID 178512967HCID 178512967, compound

Product 2

HCID 178512968HCID 178512968, compoundHCID 178512969HCID 178512969, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

Applicants have cost-effectively synthesized Agmatine Nitrate by combining nitric acid and Agmatine, mixing with water, and leaving to crystallize. Further nitratization can take place, yielding Agmatine Dinitrate or Agmatine Trinitrate. An alternative implementation comprises using Nitrous Acid (HNO2) instead of Nitric Acid (HNO3), thus yielding Agmatine Nitrite. Agmatine Nitrite has the same effects as Agmatine Nitrate, the only difference being that it requires one less step to yield Nitric Oxide (NO—). Mixed salts may also be used, such as in the non-limiting example of Agmatine Nitrate-Orotate.

Workup

  1. customleaving
  2. customto crystallize

Sources & evidence

ORD record
ord-af794fed16e9471a9b8cafbf11789ddb
Source dataset
uspto-grants-2012_05
Patent number
US08178572B2

Reaction notes

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