Methanol → 2-(t-Butyldiphenylsilyloxy)ethylamine

Reaction equation

[CH2:1]([O:2][C:3](=[O:4])[NH:10][CH2:11][CH2:12][O:13][Si:14]([c:15]1[cH:16][cH:17][cH:18][cH:19][cH:20]1)([c:21]1[cH:22][cH:23][cH:24][cH:25][cH:26]1)[C:27]([CH3:28])([CH3:29])[CH3:30])[c:5]1[cH:6][cH:7][cH:8][cH:9][cH:31]1.[CH3:32][OH:33].[OH-:34].[OH-:36].[Pd+2:35]>>[NH2:10][CH2:11][CH2:12][O:13][Si:14]([c:15]1[cH:16][cH:17][cH:18][cH:19][cH:20]1)([c:21]1[cH:22][cH:23][cH:24][cH:25][cH:26]1)[C:27]([CH3:28])([CH3:29])[CH3:30]

Participants

Reactant 4

HCID 887Methanol

HCID 961Hydroxide2×

HCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)

HCID 16221537[2-(t-Butyldiphenylsilyloxy)ethyl]carbamic acid benzyl ester

Product 1

HCID 110010432-(t-Butyldiphenylsilyloxy)ethylamine

Sources & evidence

ORD record: ord-e227dec5ea284800b906b082c832107e
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (6/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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