Ethanol → 4-(5-aminonaphthalen-1-yl)-7-(4-methylpiperazine-1-carbonyl)-9H-carbazole-1-carboxamide

HRID 192705

Reaction equation

HRID 192705 reaction equation
[Br:35][c:36]1[c:37]2[cH:38][cH:39][cH:40][c:41]([NH2:46])[c:42]2[cH:43][cH:44][cH:45]1.[C:47](=[O:48])([O-:49])[O-:50].[CH3:1][N:2]1[CH2:3][CH2:4][N:5]([C:8](=[O:9])[c:10]2[cH:11][cH:12][c:13]3[c:14]4[c:15]([B:26]5[O:27][C:28]([CH3:29])([CH3:30])[C:31]([CH3:32])([CH3:33])[O:34]5)[cH:16][cH:17][c:18]([C:23](=[O:24])[NH2:25])[c:19]4[nH:20][c:21]3[cH:22]2)[CH2:6][CH2:7]1.[CH3:53][c:54]1[cH:55][cH:56][cH:57][cH:58][cH:59]1.[CH3:60][CH2:61][OH:62].[K+:51].[K+:52]>>[CH3:1][N:2]1[CH2:3][CH2:4][N:5]([C:8](=[O:9])[c:10]2[cH:11][cH:12][c:13]3[c:14]4[c:15](-[c:36]5[c:37]6[cH:38][cH:39][cH:40][c:41]([NH2:46])[c:42]6[cH:43][cH:44][cH:45]5)[cH:16][cH:17][c:18]([C:23](=[O:24])[NH2:25])[c:19]4[nH:20][c:21]3[cH:22]2)[CH2:6][CH2:7]1

Participants

7

Reactant 6

HCID 702EthanolHCID 813Potassium Cation2×HCID 1140TolueneHCID 19660Carbonate IonHCID 190448935-Bromonaphthalen-1-amineHCID 666059127-(4-methylpiperazine-1-carbonyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-9H-carbazole-1-carboxamide

Product 1

HCID 569250334-(5-aminonaphthalen-1-yl)-7-(4-methylpiperazine-1-carbonyl)-9H-carbazole-1-carboxamide

Sources & evidence

ORD record
ord-c4a41e4300674d1ba6366f4a00cf0d83
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Linked notes

Loading…