1,4-Dioxa-8-azaspiro(4.5)decane → 8-(Imidazole-1-sulfonyl)-1,4-dioxa-8-aza-spiro[4.5]decane

HRID 1928779

Reaction equation

HRID 1928779 reaction equation
[O:1]1[C:5]2([CH2:10][CH2:9][NH:8][CH2:7][CH2:6]2)[O:4][CH2:3][CH2:2]1.FC(F)(F)S([O-])(=O)=O.[N:19]1([S:24](N2C=C[NH+](C)C2)(=[O:26])=[O:25])[CH:23]=[CH:22][N:21]=[CH:20]1>>[N:19]1([S:24]([N:8]2[CH2:9][CH2:10][C:5]3([O:4][CH2:3][CH2:2][O:1]3)[CH2:6][CH2:7]2)(=[O:26])=[O:25])[CH:23]=[CH:22][N:21]=[CH:20]1

Participants

3

Reactant 2

HCID 674351,4-Dioxa-8-azaspiro(4.5)decaneHCID 866341663-(1H-Imidazol-1-ylsulfonyl)-1-methyl-1H-imidazolium trifluoromethanesulfonate

Product 1

HCID 686401178-(Imidazole-1-sulfonyl)-1,4-dioxa-8-aza-spiro[4.5]decane

Procedure

8-(Imidazole-1-sulfonyl)-1,4-dioxa-8-aza-spiro[4.5]decane was prepared in accordance with step A of the general method described in example 76 from 1,4-dioxa-8-azaspiro(4,5)decan and 3-(1H-imidazol-1-ylsulfonyl)-1-methyl-1H-imidazolium trifluoromethanesulfonate; MS: m/e=274.5 (M+H+).

Sources & evidence

ORD record
ord-863867e99afd4d34849efa81ffc17756
Source dataset
uspto-grants-2012_05
Patent number
US08183380B2

Linked notes

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