Cyclopropanecarboxylic acid → Rac-cyclopropanecarboxylic acid [2-(6-fluoro-indan-1-ylamino)-quinolin-6-yl]-amide
Reaction equation
[F:1][C:2]1[CH:10]=[C:9]2[C:5]([CH2:6][CH2:7][CH:8]2[NH:11][C:12]2[CH:21]=[CH:20][C:19]3[C:14](=[CH:15][CH:16]=[C:17]([NH2:22])[CH:18]=3)[N:13]=2)=[CH:4][CH:3]=1.[CH:23]1([C:26](O)=[O:27])[CH2:25][CH2:24]1>>[F:1][C:2]1[CH:10]=[C:9]2[C:5]([CH2:6][CH2:7][CH:8]2[NH:11][C:12]2[CH:21]=[CH:20][C:19]3[C:14](=[CH:15][CH:16]=[C:17]([NH:22][C:26]([CH:23]4[CH2:25][CH2:24]4)=[O:27])[CH:18]=3)[N:13]=2)=[CH:4][CH:3]=1Participants
3
Procedure
The title compound was prepared in accordance with the general method 14 described in example 119 from rac-N2-(6-fluoro-indan-1-yl)-quinoline-2,6-diamine and cyclopropanecarboxylic acid; MS: m/e=362.4 (M+H−).
Sources & evidence
- ORD record
- ord-60465405ea204e2e83cb1d850fa64fe5
- Source dataset
- uspto-grants-2012_05