HuagongsheHuagongshe Chemistry Print Report · For research reference only
tert-Butyl 4-oxopiperidine-1-carboxylate → tert-Butyl 3-(3-(3-fluorophenyl)propanoyl)-4-oxopiperidine-1-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | tert-Butyl 4-oxopiperidine-1-carboxylate | HCID 735900 | — |
| Reactant | 3-(3-Fluorophenyl)propanoyl chloride | HCID 18993501 | — |
| Product | tert-Butyl 3-(3-(3-fluorophenyl)propanoyl)-4-oxopiperidine-1-carboxylate | HCID 59333733 | 48% |
Reaction Steps
tert-Butyl 3-(3-(3-fluorophenyl)propanoyl)-4-oxopiperidine-1-carboxylate (285 mg, 48%) was synthesised from tert-butyl 4-oxopiperidine-1-carboxylate and 3-(3-fluorophenyl)propanoyl chloride according to the general procedure for the preparation of diketones. MS (ES+) m/z 250 (M+H)+
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08188101B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-41125c7fb85541a8968bc3f605dc388a |
| Source note | uspto-grants-2012_05 |