Benzenesulfonyl chloride → n-[5-Hydroxy-1,5-dimethylhexyl]benzenesulphonamide

HRID 1934641

Reaction equation

Cl.[NH2:2][CH:3]([CH3:11])[CH2:4][CH2:5][CH2:6][C:7]([CH3:10])([OH:9])[CH3:8].[C:12]1([S:18](Cl)(=[O:20])=[O:19])[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1>>[OH:9][C:7]([CH3:10])([CH3:8])[CH2:6][CH2:5][CH2:4][CH:3]([NH:2][S:18]([C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1)(=[O:20])=[O:19])[CH3:11]

Participants

Reactant 2

HCID 7369Benzenesulfonyl chloride

HCID 10969Heptaminol Hydrochloride

Product 1

HCID 3746976n-[5-Hydroxy-1,5-dimethylhexyl]benzenesulphonamide

Procedure

In this case, 6-amino-2-methyl-2-heptanol hydrochloride (381.6 g, i.e. 2.1 mol) is neutralized and reacted with 353 g of benzenesulphonyl chloride (2 mol) according to Example 1(a).

Sources & evidence

ORD record: ord-afd1e7d1a0f14282846f2131210a88bb
Source dataset: uspto-grants-2002_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06384115B1

Linked notes

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