3-Methylbenzophenone → Ethyl 3-benzoylbenzoate

HRID 1935616

Reaction equation

HRID 1935616 reaction equation
CC1C=C(C=CC=1)C(C1C=CC=CC=1)=[O:6].C(N1[C:31]2[C:26](=[CH:27][CH:28]=[CH:29][CH:30]=2)[C:25]([C:32]2[CH:37]=[CH:36][CH:35]=[C:34]([C:38]([O:40][CH2:41][CH3:42])=[O:39])[CH:33]=2)=N1)C1C=CC=CC=1>>[C:25]([C:32]1[CH:33]=[C:34]([CH:35]=[CH:36][CH:37]=1)[C:38]([OH:40])=[O:39])(=[O:6])[C:26]1[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=1.[C:25]([C:32]1[CH:33]=[C:34]([CH:35]=[CH:36][CH:37]=1)[C:38]([O:40][CH2:41][CH3:42])=[O:39])(=[O:6])[C:26]1[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=1

Participants

4

Reactant 2

HCID 695113-MethylbenzophenoneHCID 99286331-Benzyl-3-(3'-ethoxycarbonylphenyl)indazole

Product 2

HCID 1013863-Benzoylbenzoic acidYield 72%HCID 14789261Ethyl 3-benzoylbenzoateYield 86.3%

Procedure

3-Methylbenzophenone was treated sequentially with the procedures (a), (b), (c), and (d) in Example 18 to obtain, in the corresponding order, 3-benzoylbenzoic acid (yield: 72%), ethyl 3-benzoylbenzoate (yield: 86.3%), and 1-benzyl-3-(3′-ethoxycarbonylphenyl)indazole in a yield of 25.5%.

Sources & evidence

ORD record
ord-aae54798193d4061beaae9c972dd7002
Source dataset
uspto-grants-2002_05
Patent number
US06387942B2

Linked notes

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