HCID 18349474, compound → 4-Methoxyphenyl 5,6-dihydroxyhexyl ether
Reaction equation
CC1(C)[O:6][CH:5]([CH2:7][CH2:8][CH2:9][CH2:10][O:11][C:12]2[CH:17]=[CH:16][C:15]([O:18][CH3:19])=[CH:14][CH:13]=2)[CH2:4][O:3]1>C(O)(=O)C>[OH:6][CH:5]([CH2:4][OH:3])[CH2:7][CH2:8][CH2:9][CH2:10][O:11][C:12]1[CH:13]=[CH:14][C:15]([O:18][CH3:19])=[CH:16][CH:17]=1Participants
3
Reactant 1
Product 1
Reagents, catalysts & solvents 1
Procedure
2.08 g of 4-methoxyphenyl 4-(2,2-dimethyldioxolan-4-yl)butyl ether from Example 1b were dissolved in 165 ml of 80% acetic acid and stirred at room temperature for 4 h. The acetic acid was separated off in vacuo, and the mixture was then coevaporated with toluene/methanol twice. This resulted in a crystalline product.
Workup
- customThe acetic acid was separated off in vacuo
- customThis resulted in a crystalline product
Sources & evidence
- ORD record
- ord-4438c891a7934e9faa0e8f722004a4b4
- Source dataset
- uspto-grants-1997_12
- Patent number
- US05696248
Reaction notes
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