N-(4-oxo-butyl)-benzamide → 1-Indan-2-yl-3-(4-oxobutyl)urea

Reaction equation

[OH:1][CH2:2][CH2:3][CH2:4][CH2:5][NH:6][C:7]([NH:9][CH:10]1[CH2:18][C:17]2[C:12](=[CH:13][CH:14]=[CH:15][CH:16]=2)[CH2:11]1)=[O:8].O=CCCCNC(=O)C1C=CC=CC=1>>[CH2:11]1[C:12]2[C:17](=[CH:16][CH:15]=[CH:14][CH:13]=2)[CH2:18][CH:10]1[NH:9][C:7]([NH:6][CH2:5][CH2:4][CH2:3][CH:2]=[O:1])=[O:8]

Participants

Reactant 2

HCID 10352536N-(4-oxo-butyl)-benzamide

HCID 669376021-(4-Hydroxybutyl)-3-indan-2-ylurea

Product 1

HCID 866513081-Indan-2-yl-3-(4-oxobutyl)urea

Procedure

1-Indan-2-yl-3-(4-oxobutyl)urea (60C) is prepared from 60B as described for 1E.

Sources & evidence

ORD record: ord-e1b84c07823f4b56a335392d8f6f4483
Source dataset: uspto-grants-2013_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08389555B2

Reaction notes

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