Methyl 2-(5-fluoro-2-methyl-1H-indol-1-yl)acetate → HCID 67044315, compound

Reaction equation

[S:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[S:6]([C:9]1[CH:16]=[CH:15][CH:14]=[CH:13][C:10]=1[CH:11]=O)(=[O:8])=[O:7].[CH3:17][O:18][C:19](=[O:32])[CH2:20][N:21]1[C:29]2[C:24](=[CH:25][C:26]([F:30])=[CH:27][CH:28]=2)[CH:23]=[C:22]1[CH3:31]>>[CH3:17][O:18][C:19](=[O:32])[CH2:20][N:21]1[C:29]2[C:24](=[CH:25][C:26]([F:30])=[CH:27][CH:28]=2)[C:23]([CH2:11][C:10]2[CH:13]=[CH:14][CH:15]=[CH:16][C:9]=2[S:6]([C:2]2[S:1][CH:5]=[CH:4][CH:3]=2)(=[O:8])=[O:7])=[C:22]1[CH3:31]

Participants

Reactant 2

HCID 58247161Methyl 2-(5-fluoro-2-methyl-1H-indol-1-yl)acetate

HCID 58564104HCID 58564104, compound

Product 1

HCID 67044315HCID 67044315, compound

Procedure

The title compound was prepared by the method of Preparation 1c using 2-(thiophene-2-sulfonyl)benzaldehyde and (5-fluoro-2-methylindol-1-yl)acetic acid methyl ester.

Sources & evidence

ORD record: ord-95a973f464e645e6b1775daa92d70924
Source dataset: uspto-grants-2013_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08394836B2

Reaction notes

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