3-Bromo-5-methylthiophene-2-carbaldehyde → 3-Benzenesulfonyl-5-methylthiophene-2-carbaldehyde

Reaction equation

Br[C:2]1[CH:6]=[C:5]([CH3:7])[S:4][C:3]=1[CH:8]=[O:9].[Na+].[C:11]1([S:17]([O-:19])=[O:18])[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1>>[C:11]1([S:17]([C:2]2[CH:6]=[C:5]([CH3:7])[S:4][C:3]=2[CH:8]=[O:9])(=[O:19])=[O:18])[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1

Participants

Reactant 2

HCID 8188853-Bromo-5-methylthiophene-2-carbaldehyde

HCID 2723840Benzenesulfinic acid, sodium salt

Product 1

HCID 866522043-Benzenesulfonyl-5-methylthiophene-2-carbaldehyde

Procedure

The title compound was prepared by the method of Preparation 7a using 3-bromo-5-methylthiophene-2-carbaldehyde and phenylsulfinic acid sodium salt.

Sources & evidence

ORD record: ord-66428ba1fc1c44309d8180e69a5e0c8c
Source dataset: uspto-grants-2013_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08394836B2

Reaction notes

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