4-Chloro-1,3-thiazole-5-carbaldehyde → 4-(Pyridine-2-sulfonyl)thiazole-5-carbaldehyde
Reaction equation
Cl[C:2]1[N:3]=[CH:4][S:5][C:6]=1[CH:7]=[O:8].[Na+].[N:10]1[CH:15]=[CH:14][CH:13]=[CH:12][C:11]=1[S:16]([O-:18])=[O:17]>>[N:10]1[CH:15]=[CH:14][CH:13]=[CH:12][C:11]=1[S:16]([C:2]1[N:3]=[CH:4][S:5][C:6]=1[CH:7]=[O:8])(=[O:18])=[O:17]Participants
3
Procedure
The title compound was prepared by the method of Preparation 42a using 4-chlorothiazole-5-carbaldehyde and pyridine-2-sulfinate sodium salt.
Sources & evidence
- ORD record
- ord-689d31502ac64accb7a38011e2cb1b28
- Source dataset
- uspto-grants-2013_03
- Patent number
- US08394836B2
Reaction notes
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