N-(1-cyano-4-(4-ethoxy-3-methylphenylsulfonamido)cyclohexyl)acetamide → HCID 67224432, compound

HRID 1944743

Reaction equation

HRID 1944743 reaction equation
[C:1]([C:3]1([NH:23][C:24](=[O:26])[CH3:25])[CH2:8][CH2:7][CH:6]([NH:9][S:10]([C:13]2[CH:18]=[CH:17][C:16](OCC)=[C:15](C)[CH:14]=2)(=[O:12])=[O:11])[CH2:5][CH2:4]1)#[N:2].NC1(C#N)CCC(NS(C2C=CC([C:44]([F:47])([F:46])[F:45])=CC=2)(=O)=O)CC1>>[C:1]([C:3]1([NH:23][C:24](=[O:26])[CH3:25])[CH2:4][CH2:5][CH:6]([NH:9][S:10]([C:13]2[CH:18]=[CH:17][C:16]([C:44]([F:47])([F:46])[F:45])=[CH:15][CH:14]=2)(=[O:12])=[O:11])[CH2:7][CH2:8]1)#[N:2]

Participants

3

Reactant 2

HCID 67223797N-(1-cyano-4-(4-ethoxy-3-methylphenylsulfonamido)cyclohexyl)acetamideHCID 67224528HCID 67224528, compound2×

Product 1

HCID 67224432HCID 67224432, compound

Procedure

Intermediate 127 was prepared by a method analogous to the method of preparing Intermediate 126 using N-(4-amino-4-cyanocyclohexyl)-4-trifluoromethyl benzenesulfonamide (Intermediate 125) as the starting material.

Sources & evidence

ORD record
ord-a5bf8b6c3dbd49bf80f437947451fd76
Source dataset
uspto-grants-2013_03
Patent number
US08394858B2

Linked notes

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