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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1946708Generated: October 24, 2026

1-Amino-4-naphthol → 6-(cyclohexylamino)-N-(4-hydroxy-1-naphthyl)pyrimidine-4-carboxamide

https://huagongshe.com/en/reaction/1946708

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Amino-4-naphtholHCID 17815—
Reactant6-(Cyclohexylamino)pyrimidine-4-carboxylic acidHCID 59447075—
Product6-(cyclohexylamino)-N-(4-hydroxy-1-naphthyl)pyrimidine-4-carboxamideHCID 25182625—

Reaction Steps

Following the general method as outlined in Example 1, starting from 6-(cyclohexylamino)pyrimidine-4-carboxylic acid (Intermediate 4) and 4-amino-1-naphtol (Aldrich), the title compound was obtained as a grey solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08399448B2
Source datasetuspto-grants-2013_03
ORD IDord-7ee0b5f55cc04565ac2444f48501834b
Source noteuspto-grants-2013_03