BrC1C=CC(S([N:11]2[CH:15]=[CH:14][C:13](/[CH:16]=[CH:17]/C(O)=O)=C2)(=O)=O)=CC=1.[C:21]([O:25][C:26](=[O:44])/[CH:27]=[CH:28]/[C:29]1[CH:33]=[CH:32][N:31]([S:34]([C:37]2[CH:42]=[CH:41][C:40](Br)=[CH:39][CH:38]=2)(=[O:36])=[O:35])[CH:30]=1)([CH3:24])([CH3:23])[CH3:22].N1C=CC=C(B(O)O)C=1.C(=O)([O-])[O-].[Na+].[Na+]>COCCOC.C1(P(C2C=CC=CC=2)C2C=CC=CC=2)C=CC=CC=1.[Pd](Cl)Cl>[C:21]([O:25][C:26](=[O:44])/[CH:27]=[CH:28]/[C:29]1[CH:33]=[CH:32][N:31]([S:34]([C:37]2[CH:42]=[CH:41][C:40]([C:16]3[CH:17]=[N:11][CH:15]=[CH:14][CH:13]=3)=[CH:39][CH:38]=2)(=[O:36])=[O:35])[CH:30]=1)([CH3:24])([CH3:23])[CH3:22]0.18 g (E)-3-[1-(4-bromo-benzenesulfonyl)-1H-pyrrol-3-yl]-acrylic acid tart-butyl ester (compound D4) and 62 mg 3-pyridylboronic acid are dissolved in 10 ml DME. A catalytic amount of bis-(triphenylphosphin-palladium (II)-chloride and 0.6 ml of an aqueous solution of sodium carbonate are added and the mixture is heated to reflux temperature overnight. The title compound is isolated by means of chromatography.
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