6-Chloro-2-phenyl-4H-3,1-benzoxazin-4-one → (2-Amino-5-chlorophenyl)(3-methoxyphenyl)methanone

HRID 1948848

Reaction equation

HRID 1948848 reaction equation
[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([Cl:8])=[CH:4][C:3]=1[C:9]([C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][C:12]=1C)=[O:10].ClC1C=CC2N=[C:24](C3C=CC=CC=3)[O:25]C(=O)C=2C=1>>[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([Cl:8])=[CH:4][C:3]=1[C:9]([C:11]1[CH:16]=[CH:15][CH:14]=[C:13]([O:25][CH3:24])[CH:12]=1)=[O:10]

Participants

3

Reactant 2

HCID 6910166-Chloro-2-phenyl-4H-3,1-benzoxazin-4-oneHCID 15592243(2-Amino-5-chlorophenyl)(2-methylphenyl)methanone

Product 1

HCID 12325894(2-Amino-5-chlorophenyl)(3-methoxyphenyl)methanoneYield 64%

Procedure

In a manner similar to that described above for compound 1m, 6-chloro-2-phenyl-benzo[d][1,3]oxazin-4-one was converted to 1s (64% yield) MS m/z=262 (M+H).

Sources & evidence

ORD record
ord-2ab5c512ce314cb8aac397a6530424c5
Source dataset
uspto-grants-2013_03
Patent number
US08399659B2

Linked notes

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