HCID 58277326, compound → HCID 58277365, compound

Reaction equation

[Cl:1][C:2]1[CH:3]=[C:4]([N:8]2[C:12]([C:13]3[CH:18]=[C:17]([C:19]([F:22])([F:21])[F:20])[CH:16]=[C:15]([F:23])[CH:14]=3)=[CH:11][C:10]([C:24]([O:26]CC)=[O:25])=[N:9]2)[CH:5]=[CH:6][CH:7]=1.ClC1C=C(N2C(C3C=C(F)C=C(Cl)C=3)=CC(C(O)=O)=N2)C=CC=1F>>[Cl:1][C:2]1[CH:3]=[C:4]([N:8]2[C:12]([C:13]3[CH:18]=[C:17]([C:19]([F:22])([F:21])[F:20])[CH:16]=[C:15]([F:23])[CH:14]=3)=[CH:11][C:10]([C:24]([OH:26])=[O:25])=[N:9]2)[CH:5]=[CH:6][CH:7]=1

Participants

Reactant 2

HCID 58277326HCID 58277326, compound

HCID 58277400HCID 58277400, compound

Product 1

HCID 58277365HCID 58277365, compound

Procedure

The preparation of the title compound takes place starting from the compound of Example 49A in analogy to the synthesis of the compound of Example 71A. 1.82 g (85% of theory) of the title compound are obtained.

Sources & evidence

ORD record: ord-a641cd4cfc434998b0b5f47978ff5463
Source dataset: uspto-grants-2013_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08399682B2

Reaction notes

Loading…