Potassium Cation → tert-butyl 2-(7-(bis((2-(trimethylsilyl)ethoxy)methyl)amino)-3-(6-phenylpyridin-3-yl)pyrazolo[1,5-a]pyrimidin-5-yl)-5-methoxy-1H-indole-1-carboxylate

HRID 195168

Reaction equation

HRID 195168 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[n:8]1[c:9]([B:19]([OH:20])[OH:21])[cH:10][c:11]2[cH:12][c:13]([O:17][CH3:18])[cH:14][cH:15][c:16]12.[Cl:30][c:31]1[n:32][c:33]2[n:34]([c:35]([N:37]([CH2:38][O:39][CH2:40][CH2:41][Si:42]([CH3:43])([CH3:44])[CH3:45])[CH2:46][O:47][CH2:48][CH2:49][Si:50]([CH3:51])([CH3:52])[CH3:53])[cH:36]1)[n:54][cH:55][c:56]2-[c:57]1[cH:58][n:59][c:60](-[c:63]2[cH:64][cH:65][cH:66][cH:67][cH:68]2)[cH:61][cH:62]1.[K+:27].[K+:28].[K+:29].[O:69]1[CH2:70][CH2:71][O:72][CH2:73][CH2:74]1.[OH2:75].[P:22]([O-:23])([O-:24])([O-:25])=[O:26]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[n:8]1[c:9](-[c:31]2[n:32][c:33]3[n:34]([c:35]([N:37]([CH2:38][O:39][CH2:40][CH2:41][Si:42]([CH3:43])([CH3:44])[CH3:45])[CH2:46][O:47][CH2:48][CH2:49][Si:50]([CH3:51])([CH3:52])[CH3:53])[cH:36]2)[n:54][cH:55][c:56]3-[c:57]2[cH:58][n:59][c:60](-[c:63]3[cH:64][cH:65][cH:66][cH:67][cH:68]3)[cH:61][cH:62]2)[cH:10][c:11]2[cH:12][c:13]([O:17][CH3:18])[cH:14][cH:15][c:16]12

Participants

7

Reactant 6

HCID 813Potassium Cation3×HCID 962WaterHCID 1061PhosphateHCID 312751,4-DioxaneHCID 27947161-Boc-5-methoxyindole-2-boronic acidHCID 866647885-chloro-3-(6-phenylpyridin-3-yl)-N,N-bis((2-(trimethylsilyl)ethoxy)methyl)pyrazolo[1,5-a]pyrimidin-7-amine

Product 1

HCID 66738101tert-butyl 2-(7-(bis((2-(trimethylsilyl)ethoxy)methyl)amino)-3-(6-phenylpyridin-3-yl)pyrazolo[1,5-a]pyrimidin-5-yl)-5-methoxy-1H-indole-1-carboxylate

Sources & evidence

ORD record
ord-c2a62eae71d04d5585de1006981c8b99
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Linked notes

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