Dimethyl Sulfoxide → 2-Chloro-4,5-difluorobenzonitrile

HRID 195216

Reaction equation

HRID 195216 reaction equation
[CH3:14][S:15]([CH3:16])=[O:17].[Cl:1][c:2]1[c:3]([C:4]#[N:5])[cH:6][c:7]([F:11])[c:8]([Cl:10])[cH:9]1.[F-:12].[K+:13].[OH2:18]>>[Cl:1][c:2]1[c:3]([C:4]#[N:5])[cH:6][c:7]([F:11])[c:8]([F:12])[cH:9]1

Participants

6

Reactant 5

HCID 679Dimethyl SulfoxideHCID 813Potassium CationHCID 962WaterHCID 28179Fluoride IonHCID 27827532,4-Dichloro-5-fluorobenzonitrile

Product 1

HCID 40858492-Chloro-4,5-difluorobenzonitrile

Sources & evidence

ORD record
ord-5182d2a03cde48129033d3dde59b5d09
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Linked notes

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