2-Chloro-1-(3,4-dimethoxyphenyl)ethanone → 2-Chloro-1-cyclopentylethanone

Reaction equation

[Cl:1][CH2:2][C:3]([C:5]1[CH:10]=[CH:9][C:8](OC)=[C:7](OC)C=1)=[O:4].ClCC(C1CC1)=O.CC1C=CC=CC=1C(=O)CCl>>[CH:5]1([C:3]([CH2:2][Cl:1])=[O:4])[CH2:10][CH2:9][CH2:8][CH2:7]1

Participants

Reactant 3

HCID 122925932-Chloro-1-(3,4-dimethoxyphenyl)ethanone

HCID 124665912-Chloro-1-cyclopropylethan-1-one

HCID 190708072-Chloro-1-(2-methylphenyl)ethan-1-one

Product 1

HCID 124665772-Chloro-1-cyclopentylethanone

Procedure

In a manner similar to that described above, 2-(chloroacethyl)furan, 2-(chloroacethyl)thiophene, 4-(chloroacetyl)-1,2-dimethoxybenzene, chloroacetyl-cyclopropane, and o-methylphenacyl chloride were prepared.

Workup

customwere prepared

Sources & evidence

ORD record: ord-2a2a86bb14f9472586257f0966f7fcfe
Source dataset: uspto-grants-1998_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05776929

Reaction notes

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