3-(4-ethylphenyl)prop-2-enoic Acid → 3-(4-ethylphenyl)propanoic Acid
Reaction equation
[CH2:1]([C:3]1[CH:13]=[CH:12][C:6]([CH:7]=[CH:8][C:9]([OH:11])=[O:10])=[CH:5][CH:4]=1)[CH3:2]>[Pd].C(O)C>[CH2:1]([C:3]1[CH:13]=[CH:12][C:6]([CH2:7][CH2:8][C:9]([OH:11])=[O:10])=[CH:5][CH:4]=1)[CH3:2]Participants
4
Reactant 1
Product 1
Reagents, catalysts & solvents 2
Procedure
An ethanol (250 ml) solution of 4-ethyl cinnamic acid (34.0 g, 0.191 mol) was hydrogenated at 60 psi over 10% Pd/C (2 g) for 2 hr. The mixture was filtered and concentrated in vacuo to give 3-(4-ethylphenyl)propionic acid as a white solid (34 g, 100%).
Workup
- filtrationThe mixture was filtered
- concentrationconcentrated in vacuo
Sources & evidence
- ORD record
- ord-0fc75f6f6b22454c91e58d00b6e81438
- Source dataset
- uspto-grants-1998_07
- Patent number
- US05780470
Reaction notes
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